Our AC Hotel by Marriott is a unique experience featuring 206 guestrooms. The City of Clayton is the premier hub of business, dining, and shopping in the St. Louis metropolitan area. Clayton is home to St. Louis County government and a collection of boutiques, galleries, hotels, and restaurants known throughout the region. At every corner in the bustling district, you’ll find places to eat, drink, shop and stay. The St. Louis area's finest attractions are within a 15-minute drive of Clayton.