Home2Suites Jacksonville- Mayo Clinic

Hotel with 125 Rooms

Home2 Suites by Hilton Jacksonville – Mayo Clinic offers a relaxed and comfortable stay near Jacksonville’s top attractions. The hotel is just minutes from Mayo Clinic, beautiful beaches, shopping at St. Johns Town Center, and a variety of dining and entertainment options. Spacious suites feature full kitchens, separate living areas, and plenty of room to unwind after a day of exploring. Guests enjoy complimentary breakfast, free Wi‑Fi, a fitness center, outdoor social spaces, and pet‑friendly accommodations. With easy access to major roadways and nearby attractions, Home2 Suites is an ideal home base for weekend getaways, family trips, and extended leisure stays.